Jundishapur Journal of Health Sciences

Published by: Kowsar

The Effect of Aerobic Exercise Training on Oxidized LDL Cholesterol (Ox-LDL) Levels and Some Cardiovascular Risk Factors in Women with Obesity

Mahtab Sadeghi 1 , Amin Mohammadi 1 , * and Ali Khajehlandi 1
Authors Information
1 Department of Physical Education, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran
Article information
  • Jundishapur Journal of Health Sciences: 11 (2); e87511
  • Published Online: April 20, 2019
  • Article Type: Research Article
  • Received: December 13, 2018
  • Revised: March 16, 2019
  • Accepted: April 9, 2019
  • DOI: 10.5812/jjhs.87511

To Cite: Sadeghi M, Mohammadi A, Khajehlandi A. The Effect of Aerobic Exercise Training on Oxidized LDL Cholesterol (Ox-LDL) Levels and Some Cardiovascular Risk Factors in Women with Obesity, Jundishapur J Health Sci. Online ahead of Print ; 11(2):e87511. doi: 10.5812/jjhs.87511.

Copyright © 2019, Jundishapur Journal of Health Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Forsythe LK, Wallace JM, Livingstone MB. Obesity and inflammation: The effects of weight loss. Nutr Res Rev. 2008;21(2):117-33. doi: 10.1017/S0954422408138732. [PubMed: 19087366].
  • 2. Zarghami N, Mohammadzadeh G, Zahedi Asl S, Hosseinpanah F. [Changes of serum leptin levels in healthy women with different grades of obesity and its correlation with hormonal and anthropometric factors]. Iran J Endocrinol Metab. 2008;10(3):227-34. Persian.
  • 3. Shavandi N, Saremi A, Shahrjerdi S, Pooryamanesh L. [Effect of ten-week aerobic training with flax seed supplementation on blood lipids profile and C- reactive protein in obese women]. J Gorgan Univ Med Sci. 2016;18(2):19-26. Persian.
  • 4. Ebrahim K, Basami M, Kolahdozi S, Karimnia SV. [The impact of resistance exercise on metabolism of fats and carbohydrates circle during endurance exercise in overweight men]. Iran J Endocrinol Metab. 2012;14(3):257-66. Persian.
  • 5. Sell H, Eckel J. Chemotactic cytokines, obesity and type 2 diabetes: In vivo and in vitro evidence for a possible causal correlation? Proc Nutr Soc. 2009;68(4):378-84. doi: 10.1017/S0029665109990218. [PubMed: 19698204].
  • 6. Robinson LE, Graham TE. Metabolic syndrome, a cardiovascular disease risk factor: Role of adipocytokines and impact of diet and physical activity. Can J Appl Physiol. 2004;29(6):808-29. [PubMed: 15630152].
  • 7. Pedersen BK. The anti-inflammatory effect of exercise: Its role in diabetes and cardiovascular disease control. Essays Biochem. 2006;42:105-17. doi: 10.1042/bse0420105. [PubMed: 17144883].
  • 8. Eftekhari M, Mozafari KH. [Effect of soybeans on homocysteine and serum lipoproteins in hyperlipidemic postmenopausal women]. Iran J Endocrinol Metab. 2008:31-9. Persian.
  • 9. Cornelissen VA, Fagard RH. Effects of endurance training on blood pressure, blood pressure-regulating mechanisms, and cardiovascular risk factors. Hypertension. 2005;46(4):667-75. doi: 10.1161/01.HYP.0000184225.05629.51. [PubMed: 16157788].
  • 10. Haghighi AH, Mahmoudi M, Delgosha H. [Hormonal responses to two programs of exhaustive resistance training of different intensities in male body builders]. Iran J Endocrinol Metab. 2012;14(3):267-74. Persian.
  • 11. Mehrabani J, Azimi B, Khosravi A, Mehrabani F. [The effect of 19 weeks of physical training on insulin resistance and high-sensitivity C-reactive protein in obese and non-obese]. Iran J Endocrinol Metab. 2011;14(5):437-44. Persian.
  • 12. Urso ML, Clarkson PM. Oxidative stress, exercise, and antioxidant supplementation. Toxicology. 2003;189(1-2):41-54. [PubMed: 12821281].
  • 13. Wang JS, Lin CC, Chen JK, Wong MK. Role of chronic exercise in decreasing oxidized LDL-potentiated platelet activation by enhancing platelet-derived no release and bioactivity in rats. Life Sci. 2000;66(20):1937-48. [PubMed: 10821118].
  • 14. Srimahachota S, Wunsuwan R, Siritantikorn A, Boonla C, Chaiwongkarjohn S, Tosukhowong P. Effects of lifestyle modification on oxidized LDL, reactive oxygen species production and endothelial cell viability in patients with coronary artery disease. Clin Biochem. 2010;43(10-11):858-62. doi: 10.1016/j.clinbiochem.2010.04.056. [PubMed: 20416290].
  • 15. Rahimi R, Jalili A. [Effect of green tea extract on serum concentration of homocysteine and Ox-LDL after resistance exercise in untrained men]. Metab Exercise Bioannual J. 2016;6(2). Persian.
  • 16. Zahabi GH, Barari AR, Ahmadi M. [Effect of concurrent on paraoxonase activity levels and some of the lipid plasma maekers in blood of women without exercise activity]. J Paramed Sci Rehabil. Persian.
  • 17. Fathei M, Khairabadi S, Ramezani F, Hejazi K. [The effects of 8-week aerobic trainings and green tea supplementation on some of the cardio-vascular risk factors in inactive overweight women]. J Q Horizon Med Sci. 2016;22(4):283-9. Persian.
  • 18. Weinbrenner T, Schroder H, Escurriol V, Fito M, Elosua R, Vila J, et al. Circulating oxidized LDL is associated with increased waist circumference independent of body mass index in men and women. Am J Clin Nutr. 2006;83(1):30-5. quiz 181-2. doi: 10.1093/ajcn/83.1.30. [PubMed: 16400046].
  • 19. Njajou OT, Kanaya AM, Holvoet P, Connelly S, Strotmeyer ES, Harris TB, et al. Association between oxidized LDL, obesity and type 2 diabetes in a population-based cohort, the health, aging and body composition study. Diabetes Metab Res Rev. 2009;25(8):733-9. doi: 10.1002/dmrr.1011. [PubMed: 19780064]. [PubMed Central: PMC3269343].
  • 20. Afzalpour ME, Gharakhanlou R, Gaeini AA, Mohebbi H, Hedayati M, Khazaei M. The effects of aerobic exercises on the serum oxidized LDL and total antioxidant capacity in non-active men. CDV Prev Control. 2008;3(2):77-82.
  • 21. Clarkson PM, Thompson HS. Antioxidants: What role do they play in physical activity and health? Am J Clin Nutr. 2000;72(2 Suppl):637S-46S. doi: 10.1093/ajcn/72.2.637S. [PubMed: 10919970].
  • 22. Kallio J, Komi P, Komulainen J, Avela J. Oxidative stress responses following acute exercise: The effect of fatness level. 12th Annual Congress of the European College of Sport Science. 11-14 July 2007; Jyvaskyla, Finland. 2007.
  • 23. Thompson PD, Lazarus B, Cullinane E, Henderson LO, Musliner T, Eshleman R, et al. Exercise, diet, or physical characteristics as determinants of HDL-levels in endurance athletes. Atherosclerosis. 1983;46(3):333-9. [PubMed: 6405759].
  • 24. Bassuk SS, Rifai N, Ridker PM. High-sensitivity C-reactive protein: Clinical importance. Curr Probl Cardiol. 2004;29(8):439-93. [PubMed: 15258556].
  • 25. Retnakaran R, Hanley AJ, Raif N, Connelly PW, Sermer M, Zinman B. C-reactive protein and gestational diabetes: The central role of maternal obesity. J Clin Endocrinol Metab. 2003;88(8):3507-12. doi: 10.1210/jc.2003-030186. [PubMed: 12915627].
  • 26. Eizadi M, Sohaily S, Khorshidi D, Samarikhalaj H. Effect of aerobic training program on serum C-reactive protein levels. Avicenna J Med Biochem. 2016;Inpress(Inpress). doi: 10.17795/ajmb-33294.
  • 27. Wong PC, Chia MY, Tsou IY, Wansaicheong GK, Tan B, Wang JC, et al. Effects of a 12-week exercise training programme on aerobic fitness, body composition, blood lipids and C-reactive protein in adolescents with obesity. Ann Acad Med Singapore. 2008;37(4):286-93. [PubMed: 18461212].
  • 28. Lakka TA, Lakka HM, Rankinen T, Leon AS, Rao DC, Skinner JS, et al. Effect of exercise training on plasma levels of C-reactive protein in healthy adults: The HERITAGE family study. Eur Heart J. 2005;26(19):2018-25. doi: 10.1093/eurheartj/ehi394. [PubMed: 15987707].
  • 29. Olson TP, Dengel DR, Leon AS, Schmitz KH. Changes in inflammatory biomarkers following one-year of moderate resistance training in overweight women. Int J Obes (Lond). 2007;31(6):996-1003. doi: 10.1038/sj.ijo.0803534. [PubMed: 17299382].
  • 30. Praet SF, Manders RJ, Lieverse AG, Kuipers H, Stehouwer CD, Keizer HA, et al. Influence of acute exercise on hyperglycemia in insulin-treated type 2 diabetes. Med Sci Sports Exerc. 2006;38(12):2037-44. doi: 10.1249/01.mss.0000235352.09061.1d. [PubMed: 17146308].
  • 31. Bonen A, Dohm GL, van Loon LJ. Lipid metabolism, exercise and insulin action. Essays Biochem. 2006;42:47-59. doi: 10.1042/bse0420047. [PubMed: 17144879].
  • 32. Javadi E, Shafaye A, Irvani A. [Sensitive of oxidized LDL between athletic and non- athletic]. Diabet Lipid J. 2003;2(2):143-6. Persian.

Featured Image:

Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments