Jundishapur Journal of Health Sciences

Published by: Kowsar

Follow-up Study of Drug Use, Depression, and Anxiety Reduction and Quality of Life in Addicts on Methadone Maintenance Therapy

Ali Almasi 1 , 2 , Behzad Hajimoradi 3 and Mitra Mohammadi 1 , 2 , *
Authors Information
1 Social Development and Health Promotion Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran
2 Department of Environmental Health Engineering, School of Public Health, Kermanshah University of Medical Sciences, Kermanshah, Iran
3 School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
Article information
  • Jundishapur Journal of Health Sciences: July 31, 2019, 11 (3); e86427
  • Published Online: August 4, 2019
  • Article Type: Research Article
  • Received: November 15, 2018
  • Revised: July 14, 2019
  • Accepted: July 27, 2019
  • DOI: 10.5812/jjhs.86427

How to Cite: Almasi A, Hajimoradi B, Mohammadi M. Follow-up Study of Drug Use, Depression, and Anxiety Reduction and Quality of Life in Addicts on Methadone Maintenance Therapy, Jundishapur J Health Sci. 2019 ; 11(3):e86427. doi: 10.5812/jjhs.86427.

Copyright © 2019, Jundishapur Journal of Health Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Berg CJ, Stratton E, Schauer GL, Lewis M, Wang Y, Windle M, et al. Perceived harm, addictiveness, and social acceptability of tobacco products and marijuana among young adults: Marijuana, hookah, and electronic cigarettes win. Subst Use Misuse. 2015;50(1):79-89. doi: 10.3109/10826084.2014.958857. [PubMed: 25268294]. [PubMed Central: PMC4302728].
  • 2. Hall W, Lynskey M. Evaluating the public health impacts of legalizing recreational cannabis use in the United States. Addiction. 2016;111(10):1764-73. doi: 10.1111/add.13428. [PubMed: 27082374].
  • 3. Oliveira J, Lopes P, Gamito P, Trigo H, Sargento P, Rosa B, et al. Neuropsychological status of heroin users undergoing methadone maintenance in harm reduction program and therapeutic community. Int J Ment Health Addict. 2015;14(2):141-8. doi: 10.1007/s11469-015-9576-8.
  • 4. Victorri-Vigneau C, Rousselet M, Grall-Bronnec M, Bouquie R, Belliot E, Guerlais M, et al. Use of psychotropic drug urine test strips in opiate maintenance therapy: A clinical assessment of its advantages. Subst Abus. 2016;37(4):584-90. doi: 10.1080/08897077.2016.1176979. [PubMed: 27093305].
  • 5. Vafaeinasab MR, Farahzadi MH, Razaghi OM, Fallahzadeh RA, Lotfi MH, Akhondzadeh S. Investigation of affecting factors on persistence in the treatment of patients under methadone maintenance therapy in addiction therapy centers, Yazd-Iran. Health. 2015;7(5):606-16. doi: 10.4236/health.2015.75072.
  • 6. Dastjerdi G, Ebrahimi Dehshiri V, Kholasezade G, Ehsani F. [Effectiveness of methadone in reduction of high risk behaviors in clients of MMT center]. Shaheed Sadoughi Univ Med Sci J. 2010;18(3):215-9. Persian.
  • 7. Raisi Dehkordi Z, Ghasab M, Golian S, Raeisi M, Chybakhsh S. [Effect of methadone on depression, anxiety and quality of life in addicts]. Ilam Univ Med Sci. 2013;22(2):132-9. Persian.
  • 8. Gholami M, Alipoor R, Zareie T, Rezaieyan F, Hedayati A. [Frequency of side effects of methadone maintenance therapy in patients referred to Fasa Doctor Shariati Hospital]. J Fasa Univ Med Sci. 2015;5(2):248-56. Persian.
  • 9. Weiner SG, Joyce AR, Thomson HN. The prevalence of nasal obstruction as a consideration in the treatment of opioid overdose. J Opioid Manag. 2017;13(2):69-76. doi: 10.5055/jom.2017.0370. [PubMed: 28829521].
  • 10. Alinejad S, Kazemi T, Zamani N, Hoffman RS, Mehrpour O. A systematic review of the cardiotoxicity of methadone. EXCLI J. 2015;14:577-600. doi: 10.17179/excli2015-553. [PubMed: 26869865]. [PubMed Central: PMC4747000].
  • 11. Sacco R, Santangelo G, Stamenova S, Bisecco A, Bonavita S, Lavorgna L, et al. Psychometric properties and validity of Beck Depression Inventory II in multiple sclerosis. Eur J Neurol. 2016;23(4):744-50. doi: 10.1111/ene.12932. [PubMed: 26782789].
  • 12. Gholami A, Araghi MT, Shamsabadi F, Bayat M, Dabirkhani F, Moradpour F, et al. Application of the World Health Organization Quality of life instrument, short form (WHOQOL-BREF) to patients with cataract. Epidemiol Health. 2016;38. e2016005. doi: 10.4178/epih/e2016005. [PubMed: 26883738]. [PubMed Central: PMC4877517].
  • 13. Potthoff S, Garnefski N, Miklósi M, Ubbiali A, Domínguez-Sánchez FJ, Martins EC, et al. Cognitive emotion regulation and psychopathology across cultures: A comparison between six European countries. Pers Individ Differ. 2016;98:218-24. doi: 10.1016/j.paid.2016.04.022.
  • 14. Tran BX, Nguyen QL, Nguyen LH, Phan HTT, Le HT, Tran TD, et al. Expanding co-payment for methadone maintenance services in Vietnam: The importance of addressing health and socioeconomic inequalities. BMC Health Serv Res. 2017;17(1):480. doi: 10.1186/s12913-017-2405-y. [PubMed: 28701208]. [PubMed Central: PMC5508786].
  • 15. Do HP, Nguyen LH, Thi Nguyen NP, Ngo C, Thi Nguyen HL, Le GT, et al. Factors associated with nicotine dependence during methadone maintenance treatment: Findings from a multisite survey in Vietnam. BMJ Open. 2017;7(7). e015889. doi: 10.1136/bmjopen-2017-015889. [PubMed: 28716791]. [PubMed Central: PMC5541583].
  • 16. Wang L, Wei X, Wang X, Li J, Li H, Jia W. Long-term effects of methadone maintenance treatment with different psychosocial intervention models. PLoS One. 2014;9(2). e87931. doi: 10.1371/journal.pone.0087931. [PubMed: 24498406]. [PubMed Central: PMC3912169].
  • 17. Corsi KF, Lehman WK, Booth RE. The effect of methadone maintenance on positive outcomes for opiate injection drug users. J Subst Abuse Treat. 2009;37(2):120-6. doi: 10.1016/j.jsat.2008.11.004. [PubMed: 19150202]. [PubMed Central: PMC2741097].
  • 18. Dhawan A, Chopra A. Does buprenorphine maintenance improve the quality of life of opioid users? Indian J Med Res. 2013;137(1):130-5. [PubMed: 23481062]. [PubMed Central: PMC3657876].
  • 19. Baharom N, Hassan MR, Ali N, Shah SA. Improvement of quality of life following 6 months of methadone maintenance therapy in Malaysia. Subst Abuse Treat Prev Policy. 2012;7:32. doi: 10.1186/1747-597X-7-32. [PubMed: 22853701]. [PubMed Central: PMC3570287].
  • 20. Behdani F, Hebrani P, Arshadi H. [Epidemiological characteristics of patients in methadone maintenance treatment, admitted in Hejazi hospital, Mashad (1384-1385)]. Quarter J Fundam Ment Health. 2007;9(33-34):53-9. Persian.
  • 21. Bosak S, Najafvand S, Mohammad Hasani S, Mazali M, Heydari Kaydan Z. [Prevalence of psychiatric disorders and related factors among addicted persons referred to withdrawal addiction centers]. Mendish J. 2015;6(10):63-72. Persian.
  • 22. Kiani Z, Mahmoodi G. [The effectiveness of methadone maintenance therapy in reducing high-risk behaviors and prevention of recurrent addiction in addicted men living in Kermanshah city in 2016]. Commun Health J. 2017;11(1):40-8. Persian.
  • 23. Wegman MP, Altice FL, Kaur S, Rajandaran V, Osornprasop S, Wilson D, et al. Relapse to opioid use in opioid-dependent individuals released from compulsory drug detention centres compared with those from voluntary methadone treatment centres in Malaysia: a two-arm, prospective observational study. Lancet Glob Health. 2017;5(2):e198-207. doi: 10.1016/S2214-109X(16)30303-5. [PubMed: 27964869]. [PubMed Central: PMC5657487].
  • 24. Cousins G, Boland F, Barry J, Lyons S, Keenan E, O'Driscoll D, et al. J-shaped relationship between supervised methadone consumption and retention in methadone maintenance treatment (MMT) in primary care: National cohort study. Drug Alcohol Depend. 2017;173:126-31. doi: 10.1016/j.drugalcdep.2016.12.009. [PubMed: 28232249].
  • 25. Chen G, Fujiwara T. Impact of one-year methadone maintenance treatment in heroin users in Jiangsu province, China. Subst Abuse Res Treat. 2009;3:61-70. doi: 10.4137/sart.s2914.
  • 26. Tavitian-Exley I, Boily MC, Heimer R, Uuskula A, Levina O, Maheu-Giroux M. Polydrug use and heterogeneity in HIV risk among people who inject drugs in estonia and Russia: A latent class analysis. AIDS Behav. 2018;22(4):1329-40. doi: 10.1007/s10461-017-1836-0. [PubMed: 28699018]. [PubMed Central: PMC5878835].
  • 27. Goldberg DM, Lin HC. Effects of the mental health parity and addictions equality act on depression treatment choice in primary care facilities. Int J Psychiatry Med. 2017;52(1):34-47. doi: 10.1177/0091217417703289. [PubMed: 28486877].
  • 28. Holmes A. Drug addictions: new insight into causes, comorbidity and potential treatments. Genes Brain Behav. 2017;16(1):5-7. doi: 10.1111/gbb.12359. [PubMed: 28097813].
  • 29. Haj Hosseini M, Hashemi R. Addicts' quality of life and psychological disorders (depression, anxiety, and stress) in two treatment methods: narcotics anonymous vs. methadone maintenance treatment. Research on Addicti. 2016;9(35):119-36.
  • 30. Peyravi H, Alavi SS, Ghanizadeh M. The effect of compliance with group therapy on quality of life, global function and care after treatment in opium addicted under MMT (methadone maintanence therapy). Iran J Nurs. 2018;30(110):45-57. doi: 10.29252/ijn.30.110.45.
  • 31. Huong AGW, Guan NC, Nordin ASA, Adlan ASA, Habil H. Quality of life assessment of opioid substance abusers on methadone maintenance therapy (MMT) in University Malaya Medical Centre. ASEAN J Psychiatry. 2009;10(1):1-11.
  • 32. Xiao L, Wu Z, Luo W, Wei X. Quality of life of outpatients in methadone maintenance treatment clinics. J Acquir Immune Defic Syndr. 2010;53 Suppl 1:S116-20. doi: 10.1097/QAI.0b013e3181c7dfb5. [PubMed: 20104102]. [PubMed Central: PMC2818825].

Featured Image:

Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments